Biosafety program plays pivotal role in the control of potentially harmful biological agents. Laboratory biosafety manual world health organization. Laboratory biosafety manual world health organization translate who publications whether for sale or for noncommercial the third edition of the who laboratory biosafety manual is a helpful reference. Cdc in cambodia strengthening laboratory biosafety and. National laboratory system center for global health. The who is a member of the united nations development group.
Stop tb partnership global laboratory initiative gli. Tuberculosis laboratory biosafety manual world health organization on. Investigations have shown that there are hundreds of unreported biosafety accidents, with laboratories selfpolicing the handling of biohazardous materials and lack of reporting. Since 1983, the world health organization who laboratory biosafety manual lbm has encouraged countries to implement basic concepts in biological safety and to develop. Laboratory biosafety status in ethiopia international. Who laboratory manual for the examination of human semen and spermcervical mucus interaction. See world health organization biosafety laboratory guidelines. Who laboratory manual for the examination and processing of. World health assembly executive board accountability. Efforts to strengthen biosafety and biosecurity in china wang qian1 the safety of facility employees and the public are best served if sites that contain, produce, store, or transfer dangerous pathogens, toxins, and bacteria have strong biosafety and biosecurity regimes in place. Harmonization of biosafety and biosecurity standards for. The training program was developed based on world health organization to the who laboratory biosafety manual of 2004 1, an. The international federation of biosafety association ifba works through. Guidance on regulations for the transport of infectious substances.
Dec 19, 2016 laboratory biosafety manual world health organization translate who publications whether for sale or for noncommercial the third edition of the who laboratory biosafety manual is a helpful reference. Laboratory biosafety is fundamental to controlling exposure to pathogens, protecting the laboratory workforce and the wider community against inadvertent exposures or releases. Apr 07, 2016 in the context of health promotion of laboratory workers, we suggest that the laboratory biosafety manual be revised and reinforced, and related prevention measures be implemented. The world health organization who has long recognized that safety and, in particular, biological safety are important international issues. Good microbiological technique and appropriate use of biosafety equipment by well trained staff remain the fundamental elements of laboratory biosafety. Iso the international organization for standardization is a worldwide. This chapter outlines the requirements for a safe environment in the clinical virology laboratory. This manual describes the minimum biosafety measures that should be implemented at the different levels of tuberculosis tb testing laboratories to reduce the risk of a laboratoryacquired infection. As mentioned in the world health organization who laboratory biosafety manual, laboratory biosafety is the term used to describe the containment principles, technologies, and practices that are. Laboratory biosafety manual third edition is a wellwritten very well organized volume that provides the reader with a clear understanding of biosafety in the laboratory.
The canadian biosafety handbook cbh, 2 nd edition, 2016 is intended as a companion document to the canadian biosafety standard cbs, 2 nd edition, 2015. Biosafety level 4 bsl4 is the highest level of biosafety precautions, and is appropriate for work with agents that could easily be aerosoltransmitted within the laboratory and cause severe to fatal disease in humans for which there are no available vaccines or treatments. Who extended biosafety advisory group bag meetings, geneva, 2425 november 2014, and 15 december 2016 key recommendation 2014 revision to the who biosafety manual is both a necessary and a priority key recommendation 2016 general agreement for the proposed modifications to the manual, the revision of which remains a priority. Who laboratory manual for the examination and processing of human semen 5th ed. For this new edition, the manual has been extensively revised and expanded. The biosafety policy applies to worker safety, public health, agricultural protection, and environmental protection. This specialized agency of the united nations published the first edition of its laboratory biosafety manual in 1983. Mar 18, 2015 issuu is a digital publishing platform that makes it simple to publish magazines, catalogs, newspapers, books, and more online. Veterinary diagnostic laboratories and necropsy, p 619646.
Who laboratory biosafety manual having served for global biosafety community hereinafter, who manual for more than 20 30 years, since it was first published in 1983, the laboratory biosafety manual has provided practical guidance on biosafety techniques for use in laboratories at all levels. Eurosurveillance mobile diagnostics in outbreak response. The manual encourages countries to prepare specific. For more than 20 years, since it was first published in 1983, the laboratory biosafety manual has provided practical guidance on biosafety techniques for use in. For more than 20 years, since it was first published in 1983, the laboratory biosafety manual has provided practical guidance on biosafety techniques for use in laboratories at all levels. A copy of any resulting product with such content should be sent to tdr, world health organization, avenue appia, 1211 geneva 27, switzerland. Biosafety and biosecurity in european containment level 3.
Developed as a quick response asset to unusual outbreaks of infectious diseases worldwide, several of these laboratories have been used as part of the world health organization response to the ebola virus outbreaks by teams of the european mobile lab project. The fifth edition includes new information on sperm preparation for clinical use or specialized assays and on cyropreservation, an expanded section on quality control in the semen analysis laboratory and evidencebased reference ranges and reference limits for various semen characteristics. The manual now covers risk assessment and safe use of recombinant dna technology, and provides guidelines for the. This biosafety manual is applicable to all laboratory, research, teaching, service, and support activities that may involveexposure to biohazard agents or materials ous or otherwisecomes under the purview of the institutional biosafety committee ibc at the university of montana. Definition of biosafety health and medical information. Globally biosafety during laboratory work and transfer of laboratory materials from one place to another is critical to prevent unintentional exposure to pathogens and toxins, or their accidental release in to the environment. Laboratory biosafety manual by world health organization. Who interim guidance on laboratory testing for coronavirus. Biosafety defines the containment conditions under which infectious agents can be safely manipulated. Since 1983, the world health organization who laboratory biosafety manual lbm has encouraged countries to implement basic concepts in biological safety and to develop national codes of practice for the safe. Risk assessment and the classification of tb laboratories 2. Who guidance on regulations for the transport of infectious substances, 20 2014 who hsegcr2012. It also highlights essential information to ensure workers and environment protection according to commonly recommended biosafety measures. Efforts to strengthen biosafety and biosecurity in china.
C 263a, to perform moderate or high complexity test. For more than 20 years, since it was first published in 1983 the laboratory biosafety manual has provided practical guidance on biosafety techniques for use in laboratories at all levels. I may be wrong, but i found particularly intriguing the fact that while the world health organization who alleged that there is no proven or standard approach to cure or improveprognosis in. Various international standards and guidelines are available for licensing or. The manual encouraged countries to accept and implement basic concepts in biological safety and to develop. All biological safety cabinets at east carolina university must be certified annually. We established a modular, rapidly deployable laboratory system that provides diagnostic support in resourcelimited, remote areas. The objective of containment is to confine biohazards and to reduce the potential.
The application of knowledge, techniques and equipment to prevent personal, laboratory and environmental exposure to potentially infectious agents or biohazards. Canadian journal of medical laboratory science 20091201. It was established on 7 april 1948, headquartered in geneva, switzerland. This manual describes the minimum biosafety measures that should be implemented at the different levels of tuberculosis tb testing laboratories to reduce the risk of a laboratory acquired infection. Good microbiological technique and appropriate use of biosafety equipment by welltrained staff remain the fundamental elements of laboratory biosafety.
Tuberculosis laboratory biosafety manual ncbi bookshelf. Laboratory biosafety is the process of applying a combination of administrative controls, containment principles, practices and procedures, safety equipment, emergency preparedness, and facilities to enable laboratory staff to work safely with potentially infectious microorganisms. In the context of health promotion of laboratory workers, we suggest that the laboratory biosafety manual be revised and reinforced, and related prevention measures be implemented. Guidelines for environmental surveillance of poliovirus circulation. Who laboratory biosafety manual lbm revision update. The laboratory biosafety manual lbm3, first published in 2004, has provided guidance to laboratory workers on how to perform laboratory work safely, to laboratory managers on how to set up a managerial approach to biosafety and to regulatory authorities, to help them consider necessary aspects for the. Its predecessor, the health organization, was an agency of the league of nations. Gli stepwise approach towards tb laboratory accreditation. Laboratory biosafety manual world health organisation staff. Enterovirus surveillance guidelines by world health. Tdr is a world health organization who executed unicef undpworld bankworld health organization special programme for research and training in tropical diseases. Bsl4 laboratories are generally set up to be either cabinet laboratories or protectivesuit laboratories.
Chapter 1620 canadian biosafety handbook, second edition. Laboratoryacquired dengue virus infection by needlestick. Efforts to strengthen biosafety and biosecurity in china wang. Results are for the detection of sars cov2 antibodies. The first edition of the world health organization who laboratory biosafety manual was published in 1983 1.
Chinese biosafety laws and regulations, including matters. Jun 27, 2014 labs are divided into 4 biosafety levels. Laboratory biosafety and biosecurity risk assessment. Refer to the who laboratory biosafety manual 3rd editionii for appropriate biosafety practices. Essential biosafety measures for tb laboratories 3. Who guidance on regulations for the transport of infectious substances, 20 2014 whohsegcr2012. Safe laboratory techniques biosafety and recombinant dna technology. To ensure performance quality for the laboratories and medical facilities in low and. There is enormous gap in biosafety use and applications between. Who laboratory biosafety manual third edition world health. Laboratory biosafety is the process of applying a combination of administrative controls, containment principles. Canadian biosafety handbook, second edition canada.
National laboratory system center for global health science. Biosafety and biosecurity center for global health. Chemical and fire safety, and decontamination and waste disposal, in addition. This begins with development of a culture of safety which identifies the risks, develops a system to mitigate these risks, and encourages ongoing evaluation of the environment and continuous risk reduction. Tuberculosis laboratory biosafety manual v executive summary following a technical consultation held between the world health organization who and the united states centers for disease control and prevention cdc in atlanta, ga, in september 2008 on strategies, approaches and partnerships that could be implemented to improve laboratory biosafety. Laboratory biosafety manual world health organisation. Apr 20, 2018 laboratory biosafety is fundamental to controlling exposure to pathogens, protecting the laboratory workforce and the wider community against inadvertent exposures or releases.
World health organization laboratory biosafety manual 2nd edition. Easily share your publications and get them in front of issuus. World health organization biosafety laboratory guildlines. Who published the first edition of the laboratory biosafety manual in 1983. Developed as a quick response asset to unusual outbreaks of infectious diseases worldwide, several of these laboratories have been used as part of the world health organization response to the ebola virus outbreaks by teams of the european mobile. Laboratory diagnosis of ebola virus disease 2 samples can be stored at room temperature for up to 24 hours.
The world health organization who has released interim guidance on laboratory testing for 2019 novel coronavirus 2019ncov in suspected human cases. The world health organization who is a specialized agency of the united nations that is concerned with international public health. Biosafety and biosecurity center for global health science. Furthermore, health authorities and health care providers in korea should be fully informed of proper dengue fever management. Laboratory improvement amendments clia of 1988, 42 u. The maximum containment laboratory biosafety level 4. Sau sokunna, deputy director, bureau of medical laboratory services in the cambodia moh, chaired the workshop, which included representatives from the world health organization who, cambodian laboratory directors, the moh legislation department, and various nongovernment organizations working within cambodias public health system. Footnote 5 it is a guidance document for canadian facilities where human and terrestrial animal pathogens are handled, that updates the guidelines originally published as part ii of the. Who laboratory manual for the examination and processing.
Orders can be placed with world health organization, who press, 1211 geneva 27. This manual is available in portuguese, french, spanish and english. Who laboratory biosafety manual world health organization. Laboratory biosecurity concepts are introduced, and the latest regulations for the transport of infectious substances are reflected.